Hepatitis treatment and prophylaxis of all hepatitis types

hepatitis treatment and prophylaxis

Hepatitis A

Treatment

Motor mode with hepatitis A treatment

Patients with hepatitis A should observe sparing regimen throughout the disease. Degree of limitation in motor mode should depend on the severity of the symptoms of intoxication, being patient and the severity of the disease. When worn out, and in most cases anicteric - milder forms mode can be obtained from the first bed days jaundice period.

Hepatitis A treatment drugs

It is believed that the majority of patients with hepatitis A is not needed any medication assignment. Gentle motoring, health food, optimal admission that preclude superinfection, especially other viral hepatitis, provide a smooth course of the disease and complete clinical recovery. Not shown for hepatitis A and glucocorticosteroid hormones.Now generally recognized that prescribe in viral hepatitis need with great caution, since their utilization and excretion in the damaged liver conditions are very difficult, can manifest their gepagotoksicheskoe action, especially when simultaneous use of multiple drugs, excluding Compatibility.It should be emphasized, however, that negative attitudes towards polypharmacy does not exclude the possibility of selective assignment of certain medications.

Clinical supervision

After discharge from the hospital all convalescents are subject to compulsory medical check-ups. Clinical examination is best done in a special cabinet, organized with the hospital.

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Hepatitis A prophylaxis

Available internationally several vaccines against hepatitis A.
All are similar in terms of how well they protect people from the virus and their side effects. For children under the age of one year no licensed vaccines.

Almost 100% of people within one month after a single dose of the vaccine developed protective levels of antibodies to the virus.Even in the case of exposure to a single dose of vaccine virus has protective effects during the two weeks after exposure to the virus. However, the manufacturers recommend two vaccine doses for longer protection for about 5-8 years after vaccination.

Postexposure prophylaxis of hepatitis A

If your environment has a patient with hepatitis, not to become infected within 2 weeks after exposure should be vaccinated against hepatitis A or an injection of immunoglobulin.

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Hepatitis B

Hepatitis B treatment

In chronic hepatitis B antiviral therapy administered in the presence of active reproduction of virions and changing the function of the liver, which are set by the analyzes. Other methods of treatment prescribed, based on the state of the liver.

The cost of chronic hepatitis B treatment depends on the chosen regimen. In mild chronic hepatitis B drugs cost per month is about $ 200, in patients with severe liver inflammation - up to $ 1,600. Accordingly, the cost of hepatitis B treatment per year will be $ 2400-19200.

Usually, when selecting regimens tailored to the particular course of hepatitis B in a particular patient, the presence of comorbidities, the financial resources of patients (different drugs with different prices, and their combination regimens).

Hepatitis B prophylaxis

In most cases it is considered an optimum one of the following two options:three-dose vaccination schedule for hepatitis B, at which the first dose (monovalent vaccine) given at birth, and the second and third dose (monovalent or combined vaccine) are provided simultaneously with the first and third doses of DPT vaccine, orscheme in which for the first dose of monovalent vaccine provided at birth, followed by 3 doses of monovalent or combined vaccine is usually given together with other vaccines in the regular childhood immunizations.The complete series of vaccinations in more than 95% of infants, children in other age groups and young people appear protective levels of antibodies. Privacy is retained for at least 20 years, and possibly for life.All previously unvaccinated children and adolescents younger than 18 years should receive the vaccine if they live in countries with low or intermediate endemicity.

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Treatment of hepatitis B in children

Certainly, hospitalized children with severe and very severe forms of hepatitis should also be hospitalized children residing in the team with the children in accordance with the epidemic testimony. Children with moderate and mild can be treated at home. If all the recommendations outcomes of hepatitis B in children in hospital and at home do not differ. It should be remembered that houses the child feels comfortable and relaxed, which is important for the healing process
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Hepatitis C

Hepatitis C treatment

The goals of hepatitis C treatment:

• Reduce or eliminate inflammation of liver, to prevent passage of hepatitis to cirrhosis.

• Reduce the amount or eliminate the virus from the body, particularly of the liver.

European Association for the Study of the Liver, including Russia, has developed basic principles of treatment of hepatitis C patients and monitor them. The basis for all regimens is interferon-alpha. mechanism of action of this preparation is to prevent the infection of new liver cells (hepatocytes).Under the influence of interferon in the body, symptoms resembling flu infection: fever, weakness. Side effects of the drug last about 12 hours after administration, and then tested. Most strongly expressed in the first two weeks of treatment. When receiving interferon need monthly blood tests to evaluate the effectiveness of treatment.Interferon can not guarantee full recovery, but to prevent the development of cirrhosis and liver cancer. The effectiveness of treatment is significantly improved if interferon is used in combination with ribavirin. A positive effect is achieved in 40-60% of cases.After hepatitis C treatment, it is important to continue to monitor blood tests over the next few months, as some patients may reappear signs of inflammation of the liver. 
Hepatitis C treatment was marked by significant advances in connection with the introduction into clinical practice of pegylated (long-acting) interferon and inhibitors of virus replication that today not only helps prevent the development of serious complications such as cirrhosis and liver cancer, but also many patients completely eliminate (remove) the pathogen, leading to recovery.

Hepatitis C prophylaxis

With the advent of mandatory preventive measures, such as testing for the virus With blood and the use of disposable syringes and surgical instruments virus infection during medical procedures has decreased, the main route of infection is the use of non-sterile needles when injecting drugs, as well as piercing and tattooing.Effective vaccine to prevent hepatitis C does not exist yet.
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Hepatitis C treatment contraindication

Currently identify several categories of people who combined antiviral treatment for hepatitis C is contraindicated:

• Patients suffering from severe general diseases, including decompensated diabetes, heart failure, coronary artery disease and pronounced hypertension, chronic obstructive pulmonary disease

• People who were transplanted kidney, heart, lung

• Patients in whom administration of interferon exacerbates the autoimmune process in the liver or other organs

• Patients with untreated hyperthyroidism (thyroid disease)

• Pregnant women

• Children under 3 years

• People with individual intolerance of any drug for the treatment of hepatitis C
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