Hepatitis B treatment and prophylaxis , let's know more about them , Hepatitis treatment

Hepatitis B treatment

Hepatitis B vaccine , Hepatitis treatment

How can hepatitis B patients be treated ?

Patients with acute hepatitis B in most cases recover on their own. In chronic hepatitis B antiviral therapy can significantly reduce the activity of viral replication, restores liver, reduces the risk of formation of cirrhosis. However, to achieve a complete cure (cleansing the body of the virus) in chronic hepatitis B with the help of modern techniques can be no more than 10-15% cases. The doctor's task - to do everything possible so that the patient was among them. Acute hepatitis B is assigned only supports detoxification and therapy aimed at the elimination of toxins and restore the liver tissue. Antiviral treatment is not carried out. In chronic hepatitis B conducted a comprehensive treatment that is individually. Special drugs are prescribed in accordance with the form and severity of the disease. For the chronic hepatitis B treatment using antiviral drugs group alpha-interferons and nucleoside analogues These drugs significantly reduce the rate of viral replication. Drugs are prescribed and separately and in combination. Selection regimen depends on the course and stage of disease. To choose the right treatment regimen can only doctor. Hepatitis B treatment may last from six months to several years. As maintenance therapy for hepatitis B can be used and some hepatoprotectors immunomodulators. Beware of false, dubious treatments. You can come across these promising advertising funds, however, the actual effectiveness of their use in hepatitis has not been proved. This applies to many tools about which states that they can activate the immune system to fight hepatitis B virus affect or improve processes in the liver. However, if the special comparative studies have been conducted, then talk about the effectiveness of these remedies can not. Anyway, remember - easy, fast and cheap chronic hepatitis B treatment options does not exist in the coming years will not appear. Drugs significantly affect the severity of liver fibrosis (other than interferon) are not yet established, although scientific research in this direction is active .

The choice of hepatitis B treatment

In chronic hepatitis B antiviral therapy administered in the presence of active reproduction of virions and changing the function of the liver, which are set by the analyzes. Other methods of treatment prescribed, based on the state of the liver. 

The cost of chronic hepatitis B treatment depends on the chosen regimen. In mild chronic hepatitis B drugs cost per month is about $ 200, in patients with severe liver inflammation - up to $ 1,600. Accordingly, the cost of hepatitis B treatment per year will be $ 2400-19200. 

Usually, when selecting regimens tailored to the particular course of hepatitis B in a particular patient, the presence of comorbidities, the financial resources of patients (different drugs with different prices, and their combination regimens

Side effects of antiviral therapy

When selecting chronic hepatitis B treatment should be prolonged, often it is not limited to a year. Side effects are rare, since this drug is well tolerated. Phenomena can be observed mild dyspepsia, rarely headache, changes in blood tests, rarely celebrated drug intolerance. If hepatitis B treatment is indicated interferons, the side effects can not be avoided, but they are predictable. After the first injection of interferon flu-like symptoms often observed. After 2-3 hours the temperature rises may be chills, muscle pain, joint pain, severe weakness. The duration of this condition can vary from a few hours to 2-3 days. Within a month the body adapts to the introduction of interferon, so that time disappears flu syndrome. Saved weakness, fatigue, but this has to be reconciled. On the second or third month of treatment may show changes in the blood count. Naturally decreases the number of leukocytes (white blood cells), platelets. It is important to monitor the extent of these changes, it is the task of the doctor. If necessary, the dose of interferon reduce or even cancel them for a certain period of time until the blood counts are restored to a safe value. Marked reduction in the number of leukocytes may facilitate adherence of bacterial infections, and low platelet count can cause hemorrhagic syndrome (bleeding). It is important to prevent these complications, so all patients receiving interferon, one must once a month without fail be to visit a doctor and perform control blood tests (complete blood count and blood chemistry). Rarer with administration of interferon may experience hair loss, depressed mood, depression, dry skin, weight loss, and in predisposed individuals thyroid dysfunction. In connection with the foregoing, it is clear that the security of the treatment - one of the main tasks of the doctor. Therefore medical observation for the treatment of interferon necessary .

What is the effectiveness of hepatitis B treatment ?

Effectiveness of hepatitis B treatment assessed by blood biochemical parameters (decreased activity of liver transaminases) and the presence of HBV-DNA in the serum, and the presence of certain markers of hepatitis B. 
If the disease is not running, there is no cirrhosis, antiviral hepatitis B treatment that helps to restore the functions of the liver cells. It is generally recommended diet with reduced fat food and substances that enhance the secretion of digestive juices (salty, spicy, fried foods, preservatives, etc.).  

Diet mostly aimed at normalizing function of the gallbladder and sphincter of Oddi, as chronic liver disease often accompanied by their work disorder (feeling of discomfort or pain in the right upper quadrant). Diet itself in the absence of cirrhosis on liver function is not affected.  

A significant change in lifestyle is required. It is only necessary to exclude alcohol and discuss use of various drugs on other comorbidities with your doctor .

Hepatitis B prophylaxis

Hepatitis B treatment and prophylaxis , Hepatitis treatment

The basis of the prevention of hepatitis B is a vaccine for hepatitis B. WHO recommends that all infants should receive the hepatitis B vaccine as soon as possible after birth, preferably within 24 hours. Dose provided at birth, should be accompanied by two or three subsequent doses to complete the vaccination series. In most cases it is considered an optimum one of the following two options: three-dose vaccination schedule for hepatitis B, at which the first dose (monovalent vaccine) given at birth, and the second and third dose (monovalent or combined vaccine) are provided simultaneously with the first and third doses of DPT vaccine, in which for the first dose of monovalent vaccine provided at birth, followed by 3 doses of monovalent or combined vaccine is usually given together with other vaccines in the regular childhood immunizations. The complete series of vaccinations in more than 95% of infants, children in other age groups and young people appear protective levels of antibodies. Privacy is retained for at least 20 years, and possibly for life. All previously unvaccinated children and adolescents younger than 18 years should receive the vaccine if they live in countries with low or intermediate endemicity. Under the conditions of these countries can acquire the infection increasing number of people from high-risk groups, so they also need to be vaccinated. These are the following groups: persons who frequently require blood or blood products, dialysis patients, individuals undergoing solid organ transplantation; persons held in prisons injecting drug users; Family members and sexual partners of people with chronic hepatitis B infection persons with multiple sexual partners, and health care workers and others who may have contact with blood and blood products by the nature of their activities, and, Travelers who have not completed the series of hepatitis B vaccination, but should offer the vaccine before traveling to endemic areas. The vaccine has a high degree of safety and efficiency. Since 1982, the world used more than one billion doses of hepatitis B vaccine in many countries, where 8% to 15% of the children had chronic hepatitis B virus infection, vaccination has reduced the rate of chronic infection in immunized children to less than 1 %. As of July 2011 the 179 member states to vaccinate infants against hepatitis B in their vaccination schedules, which is a significant progress compared with 31 in 1992, when the World Health Assembly adopted a resolution recommending that the global hepatitis B vaccination. Additionally, as at 93 July 2011 Member States have introduced providing doses of hepatitis B at birth. Implementation of strategies to ensure blood safety, including quality-assured screening of all donated blood and blood components used for transfusion, may help prevent transmission hepatitis B. Safe injection practices may protect against transmission of hepatitis B. In addition, safer sex, including minimizing the number of partners and the use of barrier methods of protection (condoms), helps protect against transmission.